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All 100 questions with answers

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  1. 1.
    Sealed ampoules containing a thermostable drug solution are commonly sterilised by
    Show answer and explanation
    Answer: B —
    Autoclave
    Sealed ampoules containing thermostable solutions are typically sterilized using moist heat under pressure (Autoclave).
  2. 2.
    The most common method used for sterilisation of vaccines among is
    Show answer and explanation
    Answer: C —
    Radiation
    Radiation is frequently used for the sterilization of heat-sensitive substances like vaccines.
  3. 3.
    The Chemical used for fumigation of rooms is
    Show answer and explanation
    Answer: A —
    Formaldehyde
    Formaldehyde is widely used as a fumigant for rooms and operation theatres.
  4. 4.
    Which among the following tablets is used in Oral cavity?
    Show answer and explanation
    Answer: B —
    Troches
    Troches (lozenges) are designed to dissolve or disintegrate slowly in the oral cavity.
  5. 5.
    The role of talc used in tablet is
    Show answer and explanation
    Answer: D —
    Both lubricant and glidant
    Talc acts as both a lubricant and a glidant in tablet manufacturing.
  6. 6.
    The polymer used for enteric coating of tablets is
    Show answer and explanation
    Answer: D —
    Polyvinyl Acetate phthalate
    Polyvinyl acetate phthalate (PVAP) is a commonly used pH-dependent polymer for enteric coating.
  7. 7.
    Which test is performed to assess the ability of the tablet to withstand abrasion in packaging, handling and transportation?
    Show answer and explanation
    Answer: B —
    Friability test
    Friability test determines the tablet's resistance to mechanical shock and abrasion.
  8. 8.
    Which of the following capsule number can accomodate maximum medicament?
    Show answer and explanation
    Answer: B —
    0
    Among the standard sizes, capsule size 0 has a larger capacity than 1, 3, or 5 (size 000 is the largest, followed by 00, 0, 1, 2, 3, 4, 5).
  9. 9.
    The term Capsule is derived from 'CAPSULA' which is a
    Show answer and explanation
    Answer: C —
    Latin term
    The word 'capsule' originates from the Latin word 'capsula', meaning a small box or chest.
  10. 10.
    Hydroxypropyl methyl cellulose can be used for/as
    Show answer and explanation
    Answer: D —
    Making empty capsule shell (vegetarian)
    HPMC (Hydroxypropyl methylcellulose) is widely used to manufacture vegetarian/hypromellose empty capsule shells.
  11. 11.
    Which of the statement is true for flocculated suspension?
    Show answer and explanation
    Answer: D —
    Rate of Sedimentation is high
    In a flocculated suspension, particles form loose aggregates leading to a high rate of sedimentation and easy redispersion.
  12. 12.
    Which among the following is a better thickening agent for suspension?
    Show answer and explanation
    Answer: B —
    Tragacanth
    Tragacanth is superior as a suspending and thickening agent compared to acacia at lower concentrations.
  13. 13.
    Which of the following emulsifying agent is from plant source?
    Show answer and explanation
    Answer: D —
    Pectin
    Pectin is a naturally occurring polysaccharide obtained from plant sources and acts as an emulsifier.
  14. 14.
    The amount of castor oil in commercial emulsion ranges from
    Show answer and explanation
    Answer: B —
    35-67%
    Commercial castor oil emulsions typically contain around 35-67% of castor oil.
  15. 15.
    Which of the following is commonly used as abrasive in tooth paste?
    Show answer and explanation
    Answer: B —
    Calcium carbonate
    Calcium carbonate is a standard polishing agent and abrasive used in toothpastes.
  16. 16.
    Which of the following cosmetic is also having the role of a drug?
    Show answer and explanation
    Answer: B —
    Anti-persipirant
    Antiperspirants are classified as cosmetics that also act as drugs because they affect physiological functions (sweat reduction).
  17. 17.
    Which of the following fixed oil is not used for parenteral preparations?
    Show answer and explanation
    Answer: A —
    Coconut oil
    Coconut oil is generally not used for parenteral formulations; sesame, peanut, and cottonseed oils are officially approved fixed oils for injections.
  18. 18.
    Hypodermic injections are administered into
    Show answer and explanation
    Answer: C —
    into loose connective and adipose tissue immediately beneath the dermal skin layer
    Hypodermic (subcutaneous) injections are administered into the subcutaneous tissue beneath the dermis.
  19. 19.
    The volume of eye drops administered from commercial eye dropper bottles is coming in the range of
    Show answer and explanation
    Answer: A —
    25 to 56 microlitre
    Commercial eye droppers typically deliver drop volumes ranging from 25 to 56 microlitres.
  20. 20.
    Phenylethyl alcohol (0.25 - 0.50% u/v) is used in opthalmic products as
    Show answer and explanation
    Answer: C —
    Preservative
    Phenylethyl alcohol is commonly added to ophthalmic formulations to serve as an antimicrobial preservative.
  21. 21.
    Which one of the following is Anthranilic Acid derivative?
    Show answer and explanation
    Answer: C —
    Furosemide
    Furosemide is a loop diuretic that chemically contains an anthranilic acid derivative structure.
  22. 22.
    A biguanide derivative which is used as an Antimalarial drug
    Show answer and explanation
    Answer: B —
    Proguanil
    Proguanil is a biguanide derivative used for the prophylaxis and treatment of malaria.
  23. 23.
    Which one of the following is used as an antifungal drug?
    Show answer and explanation
    Answer: A —
    Hamycin
    Hamycin is a polyene antifungal antibiotic used topically and orally for fungal infections.
  24. 24.
    Which of the following drug is used to arrest premature labour?
    Show answer and explanation
    Answer: D —
    Salbutamol
    Salbutamol (a beta-2 agonist) acts as atocolytic agent to relax the myometrium and arrest premature labor.
  25. 25.
    Which one of the following is an alkylating agent?
    Show answer and explanation
    Answer: A —
    Busulphan
    Busulfan is a bifunctional alkylating antineoplastic agent.
  26. 26.
    An ethylene diamine derivative used as antitubercular drug
    Show answer and explanation
    Answer: D —
    Ethambutol
    Ethambutol is a synthetic antitubercular agent that is chemically an ethylene diamine derivative.
  27. 27.
    A polyene antibiotic
    Show answer and explanation
    Answer: A —
    Amphotericin B
    Amphotericin B is a classic polyene antifungal antibiotic.
  28. 28.
    When administered with a fatty meal which drug has got better absorption
    Show answer and explanation
    Answer: D —
    Griseofulvin
    Griseofulvin is lipophilic, and its oral absorption is significantly enhanced when administered with a high-fat meal.
  29. 29.
    A cationic surfactant used as disinfectant
    Show answer and explanation
    Answer: A —
    Benzalkonium chloride
    Benzalkonium chloride is a quaternary ammonium compound acting as a cationic surfactant and disinfectant.
  30. 30.
    Cephalosporins have
    Show answer and explanation
    Answer: B —
    Beta lactam ring fused with 6 membered dihydrothiazine ring
    Cephalosporins possess a core structure consisting of a beta-lactam ring fused to a 6-membered dihydrothiazine ring.
  31. 31.
    Which is an expectorant?
    Show answer and explanation
    Answer: C —
    Potassium iodide
    Potassium iodide acts as a stimulating expectorant by increasing respiratory tract secretions.
  32. 32.
    Which is used in burns?
    Show answer and explanation
    Answer: B —
    Calcium gluconate
    Note: Official answer key marked option B, though silver nitrate/silver sulfadiazine are also used in burns.
  33. 33.
    According to Lowry bronsted theory Acid is
    Show answer and explanation
    Answer: D —
    Proton donor
    According to the Brønsted-Lowry theory, an acid is defined as a proton (extH+ext{H}^+) donor.
  34. 34.
    Antidote for cyanide poisoning
    Show answer and explanation
    Answer: C —
    Sodium Nitrite
    Sodium nitrite is a key component of the cyanide antidote kit, converting hemoglobin to methemoglobin.
  35. 35.
    Select an antitubercular agent from the following
    Show answer and explanation
    Answer: A —
    Calcium Amino salicylate
    Calcium Aminosalicylate (PAS-calcium) is a second-line antitubercular drug.
  36. 36.
    What is the concentration of iodine in Lugol's solution
    Show answer and explanation
    Answer: D —
    5% w/v
    Lugol's solution (aqueous iodine solution) typically contains 5% w/v iodine and 10% w/v potassium iodide.
  37. 37.
    A systematic acidifier
    Show answer and explanation
    Answer: B —
    Ammonium Chloride
    Ammonium chloride acts as a systemic acidifier when metabolized, increasing hydrogen ion concentration.
  38. 38.
    Which is the buffering agent in Dakin Solution?
    Show answer and explanation
    Answer: A —
    Boric acid
    Boric acid is used as a buffer in modified Dakin's solution to maintain proper alkalinity.
  39. 39.
    Which of the following element is needed for the formation of thyroid hormones?
    Show answer and explanation
    Answer: A —
    Iodine
    Iodine is an essential trace element required for the synthesis of thyroid hormones (T3 and T4).
  40. 40.
    Which of the following is used in ophthalmic preparations?
    Show answer and explanation
    Answer: B —
    Silver nitrate
    Silver nitrate solution (Credé's prophylaxis) is used in ophthalmology to prevent gonococcal ophthalmia neonatorum.
  41. 41.
    Modified Borntragers test positive for
    Show answer and explanation
    Answer: B —
    Aloe
    Modified Bornträger's test is used for the detection of C-glycosides present in drugs like Aloe.
  42. 42.
    Parquetry arrangement of cells found in
    Show answer and explanation
    Answer: C —
    Coriander
    Parquetry arrangement (mesocarp cells) is a characteristic microscopic feature of Coriander.
  43. 43.
    Shark liver oil contains
    Show answer and explanation
    Answer: A —
    Vitamin A
    Shark liver oil is primarily noted as a rich source of Vitamin A (though cod liver oil contains both A and D).
  44. 44.
    The gripping action of Laxatives reduced by
    Show answer and explanation
    Answer: C —
    Carminatives
    Carminatives are added to laxative preparations to relieve flatulence and reduce abdominal griping.
  45. 45.
    Hog weed is the synonym of
    Show answer and explanation
    Answer: D —
    Punarnava
    Punarnava (Boerhavia diffusa) is commonly known as hog weed.
  46. 46.
    Ephedrine is
    Show answer and explanation
    Answer: A —
    Adrenergic
    Ephedrine is a sympathomimetic amine commonly used as an adrenergic agonist.
  47. 47.
    Family of Ipecac
    Show answer and explanation
    Answer: B —
    Rubiaceae
    Ipecac belongs to the family Rubiaceae.
  48. 48.
    Oxytocic effect of Ergot is due to
    Show answer and explanation
    Answer: A —
    Ergometrine
    Ergometrine is the primary alkaloid responsible for the prominent oxytocic effect of ergot.
  49. 49.
    Soil nature for Cinchona cultivation is
    Show answer and explanation
    Answer: C —
    Acidic
    Cinchona plants thrive best in acidic soils rich in humus.
  50. 50.
    Primrose leaves is an adulterant of
    Show answer and explanation
    Answer: D —
    Digitalis
    Primrose leaves are commonly used as an adulterant for Digitalis leaves.
  51. 51.
    Which type diuretics cause ototoxicity when used in conjunction with aminoglycoside
    Show answer and explanation
    Answer: A —
    High ceiling diuretics
    High ceiling (loop) diuretics like furosemide can cause ototoxicity, especially when combined with aminoglycosides.
  52. 52.
    Drug causing marked extra pyramidal side effects
    Show answer and explanation
    Answer: C —
    Fluphenazine
    Typical antipsychotics like fluphenazine are associated with marked extrapyramidal side effects.
  53. 53.
    Select short acting drug is used in the diagnosis of myasthenia gravis
    Show answer and explanation
    Answer: B —
    Edrophonium
    Edrophonium is an ultra-short-acting acetylcholinesterase inhibitor used in the Tensilon test to diagnose myasthenia gravis.
  54. 54.
    Ketamine is
    Show answer and explanation
    Answer: C —
    Dissociative anaesthetic
    Ketamine produces anesthesia characterized by profound analgesia and is classified as a dissociative anesthetic.
  55. 55.
    Choose selective serotonin reuptake inhibitor used as antidepressant
    Show answer and explanation
    Answer: A —
    Escitalopram
    Escitalopram is a widely prescribed selective serotonin reuptake inhibitor (SSRI) antidepressant.
  56. 56.
    Calcium channel blockers are used for , except
    Show answer and explanation
    Answer: D —
    Bradycardia
    Calcium channel blockers can induce or worsen bradycardia, so they are not used to treat it.
  57. 57.
    Which of the following statement is incorrect about Atenolol
    Show answer and explanation
    Answer: C —
    It has short duration of action
    Atenolol is a long-acting, cardioselective beta blocker, making statement C incorrect.
  58. 58.
    Gynecomastia and menstrual irregularities are the side effects of
    Show answer and explanation
    Answer: A —
    Ketoconazole
    Ketoconazole inhibits steroidogenesis, leading to endocrine side effects such as gynecomastia and menstrual irregularities.
  59. 59.
    Select the prostaglandin analogue used for glaucoma
    Show answer and explanation
    Answer: A —
    Latanoprost
    Latanoprost is a prostaglandin F2α\alpha analogue used topically to reduce intraocular pressure in glaucoma.
  60. 60.
    Which vitamin should be administered along with isoniazid to prevent peripheral neuropathy
    Show answer and explanation
    Answer: C —
    Pyridoxine
    Pyridoxine (Vitamin B6B_6) is co-administered with isoniazid to prevent isoniazid-induced peripheral neuropathy.
  61. 61.
    How many copies of state register of pharmacists should supply to the central pharmacy council every year?
    Show answer and explanation
    Answer: A —
    5 copies
    According to pharmacy regulations, copies of the state register must be supplied as specified (5 copies).
  62. 62.
    Under the Drug and Cosmetic Act the Rules are divided into how many parts?
    Show answer and explanation
    Answer: C —
    18
    The Drugs and Cosmetics Rules are divided into 18 parts.
  63. 63.
    Keeping false accounts or making false statement under Narcotic Drugs and Psychotropic Substance Act, 1985 is punishable with
    Show answer and explanation
    Answer: D —
    Imprisonment with 5 year or fine or both
    Under the NDPS Act, maintaining false accounts or statements carries imprisonment up to 5 years or fine or both.
  64. 64.
    Sale of opium to state Govt. on manufacturing chemists can be made only from Govt. Opium factory located at
    Show answer and explanation
    Answer: D —
    Ghazipur
    Government Opium factories are located at Ghazipur and Neemuch, with Ghazipur handling specific distributions.
  65. 65.
    Which category of drugs that are prohibited to be imported
    Show answer and explanation
    Answer: C —
    Misbranded Drugs
    Misbranded, adulterated, or spurious drugs are strictly prohibited from being imported under the Drugs and Cosmetics Act.
  66. 66.
    The eligibility criteria for the PCI member, Director of central Drug Laboratory should be
    Show answer and explanation
    Answer: B —
    Ex-Officio
    The Director of the Central Drug Laboratory serves as an ex-officio member of the Pharmacy Council of India.
  67. 67.
    The label schedule X drugs contain the symbol in left hand top corner is
    Show answer and explanation
    Answer: A —
    XRx
    Schedule X drugs must be labeled with the symbol 'XRx' conspicuously on the left-top corner.
  68. 68.
    The Schedule which describes the life period of drugs is
    Show answer and explanation
    Answer: A —
    Schedule P
    Schedule P specifies the life period (expiry date) of various drugs.
  69. 69.
    When the drug labeled is not in the prescribed manner, then it is deemed to be
    Show answer and explanation
    Answer: C —
    Misbranded Drug
    A drug is considered misbranded if its label or packaging fails to follow the prescribed manner.
  70. 70.
    The advertisement of the drugs mentioned in schedule J is
    Show answer and explanation
    Answer: A —
    Prohibited
    Schedule J lists diseases and ailments which a drug may not claim to prevent or cure, and their advertisement is prohibited.
  71. 71.
    The minimum space required to open a new retail drug store is as per Drug and Cosmetic Act and Rules
    Show answer and explanation
    Answer: A —
    10 Square meters
    The minimum area required for a retail pharmacy is 10 square meters.
  72. 72.
    FIFO stands for
    Show answer and explanation
    Answer: A —
    First in First Out
    FIFO is an inventory management method where the first items to enter the stock are the first ones to be sold or used.
  73. 73.
    Purchase order or supply order is also called as
    Show answer and explanation
    Answer: B —
    Contracts
    A purchase order, once accepted by the supplier, becomes a legally binding contract.
  74. 74.
    VED Analysis is applicable in the case of
    Show answer and explanation
    Answer: D —
    Spare parts
    VED (Vital, Essential, Desirable) analysis is commonly used for inventory control of spare parts and medical supplies.
  75. 75.
    The time period between placing an order and receipt in stock is known as
    Show answer and explanation
    Answer: A —
    Lead time
    Lead time is the latency between the initiation and execution of a process, specifically the time between ordering and receiving goods.
  76. 76.
    The second step in selling process is
    Show answer and explanation
    Answer: B —
    Prospecting
    The standard selling process steps are: 1. Prospecting, 2. Pre-approach, 3. Approach, 4. Presentation, etc.
  77. 77.
    The colours have attention value in the following order for window display is
    Show answer and explanation
    Answer: A —
    Red>Orange>Yellow>Green>Blue
    Red is known to have the highest attention-grabbing value in visual merchandising.
  78. 78.
    Which technique is used for consumer based sale promotion except
    Show answer and explanation
    Answer: A —
    Credit facility
    This question was cancelled in the final answer key.
  79. 79.
    Below mentioned are tangible assets except
    Show answer and explanation
    Answer: D —
    Goodwill
    Goodwill is an intangible asset, whereas buildings, machinery, and goods are tangible assets.
  80. 80.
    The validity period for medium term finance is up to _____________
    Show answer and explanation
    Answer: D —
    3-10 years
    Medium-term finance typically refers to loans with a duration between 3 and 10 years.
  81. 81.
    "It is the usual drug reaction that cannot be explained by the inherent properties of the drug themselves but instead by some altered characteristics within the patient taking the drug" that is called as?
    Show answer and explanation
    Answer: C —
    Idiosyncrasy
    Idiosyncrasy is an abnormal, unexpected reaction to a drug that is peculiar to an individual patient.
  82. 82.
    When a drug is abruptly discontinued, it produces an intense physiological disturbance known as?
    Show answer and explanation
    Answer: D —
    Abstinence syndrome
    Abstinence syndrome (withdrawal symptoms) occurs when a drug to which a patient is dependent is suddenly stopped.
  83. 83.
    The proportion of Universal Antidote?
    Show answer and explanation
    Answer: A —
    2:1:1
    The universal antidote consists of activated charcoal (2 parts), tannic acid (1 part), and magnesium oxide (1 part).
  84. 84.
    British Anti Lewisite is otherwise known as?
    Show answer and explanation
    Answer: B —
    Dimercaprol
    British Anti-Lewisite (BAL) is the generic name for Dimercaprol, used as a chelating agent in heavy metal poisoning.
  85. 85.
    Egg Albumin is given to treat which type of poisoning?
    Show answer and explanation
    Answer: D —
    Mercury poisoning
    Egg albumin is used as an antidote for mercury poisoning as it precipitates the metal.
  86. 86.
    What do you monitor when a patient is on Furosemide and Digoxin?
    Show answer and explanation
    Answer: D —
    Hypokalaemia
    Furosemide causes potassium loss (hypokalemia), which severely increases the risk of digoxin toxicity.
  87. 87.
    The fraction of an administrated drug that reaches the systemic circulation in unchanged form from a given dosage form?
    Show answer and explanation
    Answer: A —
    Bioavailability
    Bioavailability measures the rate and extent to which the active drug reaches systemic circulation.
  88. 88.
    A Seizure episode can be measured by using
    Show answer and explanation
    Answer: B —
    EEG
    Electroencephalogram (EEG) records electrical activity of the brain to diagnose and monitor seizures.
  89. 89.
    In which condition, the level of urinary diastase activity increases?
    Show answer and explanation
    Answer: C —
    Pancreatitis
    Urinary diastase (amylase) levels increase significantly during acute pancreatitis.
  90. 90.
    Who will acts as the Chairman in PTC?
    Show answer and explanation
    Answer: D —
    Physician
    A senior physician typically serves as the chairperson of the Pharmacy and Therapeutics Committee (PTC).
  91. 91.
    Name the Hospital, in which the first Hospital Formulary for a Government teaching Hospital in India is published in 1997?
    Show answer and explanation
    Answer: B —
    Govt. Medical College, Thiruvananthapuram
    Government Medical College, Thiruvananthapuram published the first hospital formulary for a government teaching hospital in India in 1997.
  92. 92.
    Name the publication, published by the Drug information centre?
    Show answer and explanation
    Answer: A —
    Drug information bulletin
    Drug Information Centers frequently publish a regular 'Drug Information Bulletin' for healthcare professionals.
  93. 93.
    Which of the following T ube is used to feed the patient?
    Show answer and explanation
    Answer: C —
    Ryle's T ube
    Ryle's tube is a nasogastric tube commonly used for enteral feeding and gastric aspiration.
  94. 94.
    Example for inpatient Drug distribution system?
    Show answer and explanation
    Answer: A —
    UDDS
    Unit Dose Drug Distribution System (UDDS) is a standard inpatient drug distribution method.
  95. 95.
    Depreciation of machines and building are comes under which category of cost in Manufacturing of drugs?
    Show answer and explanation
    Answer: C —
    Indirect cost
    Depreciation on fixed assets like buildings and machinery is classified as an indirect cost/overhead.
  96. 96.
    Abbreviation of HEPA?
    Show answer and explanation
    Answer: D —
    High Efficiency Particulate Air
    HEPA stands for High Efficiency Particulate Air filter.
  97. 97.
    "Sham" test is used to detect?
    Show answer and explanation
    Answer: A —
    Pyrogens
    In pyrogen testing (rabbit test), a 'sham' test or control procedure is employed to account for baseline temperature variations.
  98. 98.
    "MEDIPHOR" is the computerised service offered by a Drug information system to Monitor?
    Show answer and explanation
    Answer: C —
    Drug interactions
    MEDIPHOR (Monitoring Environment for Drugs in Hospital Oriented Research) was a computerized system designed to monitor adverse drug reactions and drug interactions.
  99. 99.
    Antidote for Iron poisoning
    Show answer and explanation
    Answer: D —
    Desferrioxamine
    Desferrioxamine is a specific chelating agent used as an antidote for acute iron poisoning.
  100. 100.
    The consumption of a drug repeatedly to produce profound effect on mood, and feeling of well-being are called as?
    Show answer and explanation
    Answer: B —
    Drug abuse
    Drug abuse refers to the non-medical, repetitive use of a substance to alter mood or induce euphoria.

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